{"id":175389,"date":"2026-10-19T09:12:56","date_gmt":"2026-10-19T09:12:56","guid":{"rendered":"https:\/\/www.m3globalresearch.com\/blog\/?p=175389"},"modified":"2026-10-20T14:49:58","modified_gmt":"2026-10-20T14:49:58","slug":"camera-based-imaging-technique-offers-objective-assessment-of-skin-fibrosis-in-scleroderma","status":"publish","type":"post","link":"https:\/\/www.m3globalresearch.com\/blog\/camera-based-imaging-technique-offers-objective-assessment-of-skin-fibrosis-in-scleroderma\/","title":{"rendered":"Camera-Based Imaging Technique Offers Objective Assessment of Skin Fibrosis in Scleroderma"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"175389\" class=\"elementor elementor-175389\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7b2c08d e-con e-atomic-element e-flexbox-base e-d693f31 \" data-id=\"7b2c08d\" data-element_type=\"e-flexbox\" data-e-type=\"e-flexbox\" data-interaction-id=\"7b2c08d\">\n    \t\t<div class=\"elementor-element elementor-element-b12c334 elementor-widget elementor-widget-text-editor\" data-id=\"b12c334\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Researchers have developed and tested a non-invasive, camera-based technique to assess skin changes in patients with scleroderma, potentially replacing the subjective manual examination that has been standard practice for more than 50 years.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f241f77 elementor-widget elementor-widget-text-editor\" data-id=\"f241f77\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Scleroderma (systemic sclerosis) is a rare, chronic autoimmune disease that causes excessive collagen production, leading to hardening and thickening of the skin and internal organs. Physicians currently assess skin involvement by manually pinching the skin, but this approach is subjective and can vary between clinicians, making it difficult to track disease progression or treatment response accurately.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bcdb794 elementor-widget elementor-widget-text-editor\" data-id=\"bcdb794\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The technique, called spatial frequency domain imaging (SFDI), works by shining patterns of harmless light onto the skin and measuring how the light reflects back. Researchers from Boston University School of Medicine and the Department of Biomedical Engineering studied 49 scleroderma patients and 25 healthy volunteers, imaging six sites across the hands, forearms, and fingers.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c1081fb elementor-widget elementor-widget-text-editor\" data-id=\"c1081fb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Light readings were consistently lower in scleroderma patients compared with healthy individuals. Lower readings correlated with higher clinical skin scores, increased scarring in biopsies and greater skin thickness on ultrasound. Notably, the technique detected differences even in skin that clinicians had scored as normal, suggesting SFDI may identify subtle changes before they become apparent on standard examination.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-05d7226 elementor-widget elementor-widget-text-editor\" data-id=\"05d7226\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The findings could address a significant barrier in scleroderma research. Currently, no therapies are specifically approved for skin fibrosis in this condition, partly because imprecise measurement methods can make beneficial treatments appear ineffective in clinical trials.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0b60924 elementor-widget elementor-widget-text-editor\" data-id=\"0b60924\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The researchers suggest this fast, painless, non-contact approach could help clinicians track skin changes more objectively and enable clinical trials to detect treatment benefits more reliably.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bb5aaf1 elementor-widget elementor-widget-text-editor\" data-id=\"bb5aaf1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Source: Bujor A et al. Spatial frequency domain imaging for assessment of skin fibrosis in systemic sclerosis: a prospective cohort study. The Lancet Rheumatology (2026). DOI: 10.1016\/S2665-9913(26)00229-8<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\n<\/div>\n\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Researchers test non-invasive imaging to assess skin changes in scleroderma patients, offering a more objective alternative to manual exams.<\/p>\n","protected":false},"author":11,"featured_media":175424,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","footnotes":""},"categories":[3200],"tags":[],"class_list":["post-175389","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-medical-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.9 (Yoast SEO v28.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Camera-Based Imaging Technique Offers Objective Assessment of Skin Fibrosis in Scleroderma<\/title>\n<meta name=\"description\" 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