{"id":169165,"date":"2026-04-13T16:03:38","date_gmt":"2026-04-13T15:03:38","guid":{"rendered":"https:\/\/m3globalresearch.blog\/?p=169165"},"modified":"2026-04-13T16:03:38","modified_gmt":"2026-04-13T15:03:38","slug":"blood-test-shows-promise-detecting-multiple-cancers-diseases","status":"publish","type":"post","link":"https:\/\/www.m3globalresearch.com\/blog\/blood-test-shows-promise-detecting-multiple-cancers-diseases\/","title":{"rendered":"Blood Test Shows Promise for Detecting Multiple Cancers and Diseases Simultaneously","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"169165\" class=\"elementor elementor-169165\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bb4b1a5 e-flex e-con-boxed e-con e-parent\" data-id=\"bb4b1a5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-26551cc elementor-widget elementor-widget-text-editor\" data-id=\"26551cc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tUCLA scientists have developed a blood test that shows early promise in detecting multiple cancers and various organ conditions from a single sample by analysing DNA fragments circulating in the bloodstream. The findings were published in <em>Proceedings of the National Academy of Sciences<\/em>.\n<br><br>\nThe method, called MethylScan, analyses cell-free DNA (cfDNA) &#8211; genetic material released into the blood when cells die. Rather than searching for genetic mutations, the test examines DNA methylation patterns, chemical tags that regulate gene activity and differ by tissue type, changing when cells become cancerous or diseased.\n<br><br>\nA key challenge is that 80 to 90% of cfDNA originates from normal blood cells, creating background noise. To address this, researchers developed a technique using specialised enzymes to selectively remove unmethylated DNA fragments from blood cells, enriching samples for methylated DNA from solid organs. This reduces sequencing requirements and costs whilst maintaining sensitivity.\n<br><br>\nThe team tested MethylScan on blood samples from 1,061 individuals, including patients with liver, lung, ovarian, and stomach cancers, various liver diseases, benign lung nodules, and healthy participants. At 98% specificity, the test detected approximately 63% of cancers across all stages and 55% of early-stage cancers. For liver cancer surveillance in high-risk individuals, detection reached nearly 80% at over 90% specificity.\n<br><br>\nThe methylation patterns also helped identify tissue of origin &#8211; important for directing follow-up imaging to the correct organ. Additionally, the test distinguished between different liver disease types with approximately 85% accuracy, potentially reducing the need for invasive biopsies.\n<br><br>\nSenior author Dr Jasmine Zhou noted that larger prospective trials are needed but described the work as an important step towards affordable, comprehensive disease screening.\n<br><br>\n<strong>Source:<\/strong> Medical Xpress \/ UCLA (PNAS, 2026)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-60ea1e7 e-con-full e-flex e-con e-child\" data-id=\"60ea1e7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c06b1f7 elementor-share-buttons--view-icon elementor-share-buttons--skin-minimal elementor-share-buttons--shape-circle elementor-share-buttons--color-custom elementor-grid-0 elementor-widget elementor-widget-share-buttons\" data-id=\"c06b1f7\" 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8.447.974 16.568 1.299 25.34 1.299 49.055 0 94.213-16.568 130.274-44.832-46.132-.975-84.792-31.188-98.112-72.772 6.498.974 12.995 1.624 19.818 1.624 9.421 0 18.843-1.3 27.614-3.573-48.081-9.747-84.143-51.98-84.143-102.985v-1.299c13.969 7.797 30.214 12.67 47.431 13.319-28.264-18.843-46.781-51.005-46.781-87.391 0-19.492 5.197-37.36 14.294-52.954 51.655 63.675 129.3 105.258 216.365 109.807-1.624-7.797-2.599-15.918-2.599-24.04 0-57.828 46.782-104.934 104.934-104.934 30.213 0 57.502 12.67 76.67 33.137 23.715-4.548 46.456-13.32 66.599-25.34-7.798 24.366-24.366 44.833-46.132 57.827 21.117-2.273 41.584-8.122 60.426-16.243-14.292 20.791-32.161 39.308-52.628 54.253z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1e789dc e-flex e-con-boxed e-con e-parent\" data-id=\"1e789dc\" 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data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Participate in Paid Oncology Surveys\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8a19a82 elementor-widget elementor-widget-spacer\" data-id=\"8a19a82\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9437010 e-flex e-con-boxed e-con e-parent\" data-id=\"9437010\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-1b7a48b e-con-full e-flex e-con e-child\" data-id=\"1b7a48b\" data-element_type=\"container\" 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potential.<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":169253,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[3200,1],"tags":[2875],"class_list":["post-169165","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-medical-news","category-uncategorized","tag-oncology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Blood Test Shows Promise for Detecting Multiple Cancers and Diseases<\/title>\n<meta name=\"description\" content=\"Blood test using dna fragments in bloodstream shows promise for detecting multiple cancers early with improved diagnostic potential.\" \/>\n<meta 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