{"id":167948,"date":"2026-03-06T14:19:45","date_gmt":"2026-03-06T14:19:45","guid":{"rendered":"https:\/\/m3globalresearch.blog\/?p=167948"},"modified":"2026-03-06T14:19:45","modified_gmt":"2026-03-06T14:19:45","slug":"glp-1-medications-may-reduce-substance-use-disorders","status":"publish","type":"post","link":"https:\/\/www.m3globalresearch.com\/blog\/glp-1-medications-may-reduce-substance-use-disorders\/","title":{"rendered":"GLP-1 Medications Linked to Reduced Risk of Substance Use Disorders, Large Study Finds","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"167948\" class=\"elementor elementor-167948\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8bd5338 e-flex e-con-boxed e-con e-parent\" data-id=\"8bd5338\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-538df88 elementor-widget elementor-widget-text-editor\" data-id=\"538df88\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>A large observational study has found that GLP-1 receptor agonist medications may reduce the risk of developing multiple substance use disorders and lower the likelihood of serious harm in those already affected.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-42d7431 elementor-widget elementor-widget-text-editor\" data-id=\"42d7431\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\">The analysis, published in <em>The BMJ<\/em>, examined electronic health records from more than 600,000 United States Veterans Affairs patients with type 2 diabetes over three years. Researchers compared patients treated with GLP-1 drugs against those receiving other blood sugar-lowering medications across seven parallel trials covering alcohol, cannabis, cocaine, nicotine, and opioid use.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c7ba5c5 elementor-widget elementor-widget-text-editor\" data-id=\"c7ba5c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Patients taking GLP-1 medications showed reduced risks of developing addiction across all substances studied: 18% lower for alcohol, 14% for cannabis, 20% for both cocaine and nicotine, and 25% for opioids. Among patients with existing substance use disorders, GLP-1 use was associated with a 31% lower risk of emergency department visits, a 39% lower risk of overdose, and a 50% lower risk of death.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7844ced elementor-widget elementor-widget-text-editor\" data-id=\"7844ced\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Researchers suggest the drugs may act on the brain&#8217;s reward pathways, the same system that drives cravings, in a manner analogous to their known effect of reducing intrusive thoughts about food. However, as an observational study, the findings demonstrate association rather than causation.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad701be elementor-widget elementor-widget-text-editor\" data-id=\"ad701be\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\">The study&#8217;s limitations include a population that is predominantly older, white, and male, and data drawn exclusively from patients with diabetes. Experts stress that the results do not yet justify prescribing GLP-1 drugs specifically to prevent or treat addiction; randomised controlled trials are needed before clinical recommendations can be made.<\/p>\n<p class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"><em>Published in: The BMJ<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-09e6995 e-con-full e-flex e-con e-child\" data-id=\"09e6995\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ac7fbf5 elementor-share-buttons--view-icon elementor-share-buttons--skin-minimal elementor-share-buttons--shape-circle elementor-share-buttons--color-custom elementor-grid-0 elementor-widget elementor-widget-share-buttons\" data-id=\"ac7fbf5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"share-buttons.default\">\n\t\t\t\t\t\t\t<div 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disorders.<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":168115,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[3200],"tags":[8276,178,7424,8277],"class_list":["post-167948","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-medical-news","tag-glp-1-medications","tag-medical-news","tag-psychiatry","tag-substance-use-disorders"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>GLP-1 Medications Linked to Reduced Risk of Substance Use Disorders<\/title>\n<meta name=\"description\" content=\"Study finds GLP-1 Medications linked to lower risk of substance use disorders and 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